FDA animal and veterinary adverse event reports, newest first. All filters optional. Each record includes AER ID, dates, animal species/gender/breed/age/weight, reactions (VeDDRA-coded), drugs (brand + active ingredients + administration), primary reporter (Veterinarian/Owner/Other). Use cases: veterinary practice safety research, pet food adverse events, livestock drug surveillance. Backed by OpenFDA's /animalandveterinary/event endpoint; public-domain US government records.
/api/gov/fda-animalvet-eventsPAYMENT-SIGNATURE.The fda animalvet events API is a pay-per-call gov endpoint built for AI agents and autonomous software. FDA animal and veterinary adverse event reports, newest first.
There is no signup and no API key. An agent (or any HTTP client) hits the endpoint, receives an x402 "402 Payment Required" challenge, signs a sub-cent USDC payment on Base or Solana, and retries — the data comes back on the paid request. That makes it a drop-in fda animalvet events data source for an agent tool-use loop, an MCP host, or a backend that needs gov data on demand without onboarding to yet another vendor portal.
| Name | Type | Description |
|---|---|---|
drug | string | Drug name substring across brand + active ingredients. Examples: "Heartgard", "Bravecto", "Apoquel". min 2 chars · max 100 chars |
species | string | Animal species. Examples: "Dog", "Cat", "Horse", "Cattle", "Chicken". min 2 chars · max 60 chars |
reaction | string | Reaction (VeDDRA preferred term) substring. Examples: "Vomiting", "Lethargy", "Death". min 2 chars · max 100 chars |
limit | integer | Max events (1-100). Default 20. min 1 · max 100 |
# 1. Probe with no auth → 402 envelope with PaymentRequirements curl -sS 'https://2s.io/api/gov/fda-animalvet-events?drug=xx&species=xx&reaction=xx&limit=20' # 2. Sign + retry with PAYMENT-SIGNATURE: curl -sS 'https://2s.io/api/gov/fda-animalvet-events?drug=xx&species=xx&reaction=xx&limit=20' \ -H 'PAYMENT-SIGNATURE: <base64-json-payload>' # Or use the canonical runner (handles probe → sign → retry): # EVM_PRIVATE_KEY=0x... node --env-file=.env.local \ # --experimental-strip-types scripts/x402-pay.ts \ # 'https://2s.io/api/gov/fda-animalvet-events?drug=xx&species=xx&reaction=xx&limit=20'
import { TwoS } from '@2sio/sdk'
const client = new TwoS({
privateKey: process.env.EVM_PRIVATE_KEY as `0x${string}`,
})
const result = await client.gov.fdaAnimalvetEvents({
"drug": "xx",
"species": "xx",
"reaction": "xx",
"limit": 20
})
console.log('endpoint:', result.endpoint)
console.log('cost:', result.costUsd, 'USDC')
console.log('tx:', result.settlement?.txHash)
console.log('data:', result.data)import os
from twosio import TwoS
client = TwoS(private_key=os.environ["EVM_PRIVATE_KEY"])
result = client.gov.fda_animalvet_events(drug="xx", species="xx", reaction="xx", limit=20)
print("endpoint:", result.endpoint)
print("cost:", result.cost_usd, "USDC")
print("tx:", (result.settlement or {}).get("tx_hash"))
print("data:", result.data)// 1. Add @2sio/mcp to your MCP host config (Claude Desktop example below).
// EVM_PRIVATE_KEY funds x402 payments per call.
// claude_desktop_config.json
{
"mcpServers": {
"2sio": {
"command": "npx",
"args": ["-y", "@2sio/mcp"],
"env": { "EVM_PRIVATE_KEY": "0x..." }
}
}
}
// 2. Once the server is running, agents call this tool via standard MCP:
{
"jsonrpc": "2.0",
"id": 1,
"method": "tools/call",
"params": {
"name": "gov.fda-animalvet-events",
"arguments": {
"drug": "xx",
"species": "xx",
"reaction": "xx",
"limit": 20
}
}
}| Field | Type | Description |
|---|---|---|
ok | boolean | one of: true |
items | array | |
total | integer | Total matching rows upstream; null when unknown. |
source | object | |
meta | object |
{
"ok": true,
"items": [
{
"aerId": "example",
"originalReceiveDate": "example",
"onsetDate": "example",
"numberAffected": 1,
"numberTreated": 1,
"animal": {
"species": "example",
"gender": "example",
"breed": "example",
"ageValue": "example",
"ageUnit": "example",
"weightValue": "example",
"weightUnit": "example"
},
"reactions": [
{
"term": "example",
"veddraCode": "example"
}
],
"drugs": [
{
"brandName": "example",
"activeIngredients": [
"example"
],
"administeredBy": "example",
"route": "example"
}
],
"primaryReporter": "example"
}
],
"total": 1,
"source": {
"provider": "example",
"url": "example",
"license": "example"
},
"meta": {
"query": {
"drug": "example",
"species": "example",
"reaction": "example",
"limit": 1
}
}
}