Look up US drug pricing from CMS NADAC (National Average Drug Acquisition Cost) — the benchmark per-unit acquisition cost CMS surveys from retail pharmacies and publishes weekly. Pass ndc (11-digit National Drug Code) for an exact product, or name (drug name/description keyword, e.g. 'atorvastatin 10 mg') to search. Returns rows with the NDC, description, nadacPerUnit (USD per pricing unit), pricingUnit (EA/ML/GM), effectiveDate, OTC flag, and brand/generic classification — most recent effective date first. Real surveyed acquisition costs instead of model-guessed prices. Public domain; the current-year dataset is resolved automatically. NADAC is an acquisition-cost benchmark, not a retail or insured price.
/api/medical/drug-pricePAYMENT-SIGNATURE.The drug price API is a pay-per-call medical endpoint built for AI agents and autonomous software. Look up US drug pricing from CMS NADAC (National Average Drug Acquisition Cost) — the benchmark per-unit acquisition cost CMS surveys from retail pharmacies and publishes weekly.
There is no signup and no API key. An agent (or any HTTP client) hits the endpoint, receives an x402 "402 Payment Required" challenge, signs a sub-cent USDC payment on Base or Solana, and retries — the data comes back on the paid request. That makes it a drop-in drug price data source for an agent tool-use loop, an MCP host, or a backend that needs medical data on demand without onboarding to yet another vendor portal.
| Name | Type | Description |
|---|---|---|
ndc | string | min 3 chars · max 20 chars |
name | string | min 2 chars · max 80 chars |
limit | integer | min 1 · max 100 |
# 1. Probe with no auth → 402 envelope with PaymentRequirements curl -sS 'https://2s.io/api/medical/drug-price?ndc=xxx&name=xx&limit=1' # 2. Sign + retry with PAYMENT-SIGNATURE: curl -sS 'https://2s.io/api/medical/drug-price?ndc=xxx&name=xx&limit=1' \ -H 'PAYMENT-SIGNATURE: <base64-json-payload>' # Or use the canonical runner (handles probe → sign → retry): # EVM_PRIVATE_KEY=0x... node --env-file=.env.local \ # --experimental-strip-types scripts/x402-pay.ts \ # 'https://2s.io/api/medical/drug-price?ndc=xxx&name=xx&limit=1'
import { TwoS } from '@2sio/sdk'
const client = new TwoS({
privateKey: process.env.EVM_PRIVATE_KEY as `0x${string}`,
})
const result = await client.medical.drugPrice({
"ndc": "xxx",
"name": "xx",
"limit": 1
})
console.log('endpoint:', result.endpoint)
console.log('cost:', result.costUsd, 'USDC')
console.log('tx:', result.settlement?.txHash)
console.log('data:', result.data)import os
from twosio import TwoS
client = TwoS(private_key=os.environ["EVM_PRIVATE_KEY"])
result = client.medical.drug_price(ndc="xxx", name="xx", limit=1)
print("endpoint:", result.endpoint)
print("cost:", result.cost_usd, "USDC")
print("tx:", (result.settlement or {}).get("tx_hash"))
print("data:", result.data)// 1. Add @2sio/mcp to your MCP host config (Claude Desktop example below).
// EVM_PRIVATE_KEY funds x402 payments per call.
// claude_desktop_config.json
{
"mcpServers": {
"2sio": {
"command": "npx",
"args": ["-y", "@2sio/mcp"],
"env": { "EVM_PRIVATE_KEY": "0x..." }
}
}
}
// 2. Once the server is running, agents call this tool via standard MCP:
{
"jsonrpc": "2.0",
"id": 1,
"method": "tools/call",
"params": {
"name": "medical.drug-price",
"arguments": {
"ndc": "xxx",
"name": "xx",
"limit": 1
}
}
}| Field | Type | Description |
|---|---|---|
ok | boolean | one of: true |
items | array | |
total | integer | Total matching rows upstream; null when unknown. |
source | object | |
meta | object |
{
"ok": true,
"items": [
{
"ndc": "example",
"description": "example",
"nadacPerUnit": 1,
"pricingUnit": "example",
"effectiveDate": "example",
"otc": false,
"classification": "example",
"asOfDate": "example"
}
],
"total": 1,
"source": {
"provider": "example",
"url": "example",
"license": "example"
},
"meta": {
"query": {
"ndc": "example",
"name": "example"
},
"datasetYear": "example",
"total": 1
}
}